Plant Transcription Factor Database
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G28770.3
Common NameAtbZIP63, BZO2H3
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bZIP
Protein Properties Length: 250aa    MW: 27233.4 Da    PI: 6.2973
Description bZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G28770.3genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
       bZIP_1   4 lkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkke 55 
                  +kr +r+ +NRe+ArrsR+RK+a + eLe+ v +L  eN++L k l   +++
                  79****************************************9988777665 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM003381.5E-17149213IPR004827Basic-leucine zipper domain
PROSITE profilePS5021710.921151214IPR004827Basic-leucine zipper domain
PfamPF001701.1E-13152199IPR004827Basic-leucine zipper domain
SuperFamilySSF579593.38E-12152203No hitNo description
Gene3DG3DSA: hitNo description
PROSITE patternPS000360156171IPR004827Basic-leucine zipper domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0071215Biological Processcellular response to abscisic acid stimulus
GO:0071333Biological Processcellular response to glucose stimulus
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0042802Molecular Functionidentical protein binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009052anatomyflower pedicel
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 250 aa     Download sequence    Send to blast
Nucleic Localization Signal ? help Back to Top
No. Start End Sequence
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.157540.0leaf| root| seed| silique
Expression -- Microarray ? help Back to Top
Source ID E-value
Expression AtlasAT5G28770-
Functional Description ? help Back to Top
Source Description
TAIRbZIP protein BZO2H3 mRNA, partial cds
Function -- GeneRIF ? help Back to Top
  1. Data show that phosphorylation-mimicking serine substitutions strongly interfere with the DNA binding of two prototypical Arabidopsis bZIPs, namely AtZIP63 and HY5.
    [PMID: 20047775]
  2. Data show that AtbZIP1 can bind ACGT-based motifs in vitro and that the binding characteristics appear to be affected by the heterodimerization between AtbZIP1 and the C-group AtbZIPs, including AtbZIP10 and AtbZIP63.
    [PMID: 20080816]
  3. AtbZIP63 is an important node of the glucose-abscisic acid interaction network.
    [PMID: 21844310]
  4. ARR18 interaction negatively interferes with the transcriptional activity of bZIP63 on the PDH1 promoter.
    [PMID: 24948556]
  5. Phosphorylation of bZIP63 by SnRK1 changed its dimerization preference, thereby affecting target gene expression and ultimately primary metabolism.
    [PMID: 26263501]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
Motif logo
Cis-element ? help Back to Top
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
Interaction ? help Back to Top
Source Intact With
BioGRIDAT5G28770, AT5G49450, AT5G58080, AT1G75390
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G28770
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3171690.0AK317169.1 Arabidopsis thaliana AT5G28770 mRNA, complete cds, clone: RAFL21-54-H13.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001031962.10.0basic leucine zipper 63
SwissprotB9DGI81e-166BZP63_ARATH; Basic leucine zipper 63
TrEMBLD7M6Y61e-141D7M6Y6_ARALL; Putative uncharacterized protein
STRINGAT5G28770.21e-164(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
  2. Jakoby M, et al.
    bZIP transcription factors in Arabidopsis.
    Trends Plant Sci., 2002. 7(3): p. 106-11
  3. Vincentz M,Bandeira-Kobarg C,Gauer L,Schl
    Evolutionary pattern of angiosperm bZIP factors homologous to the maize Opaque2 regulatory protein.
    J. Mol. Evol., 2003. 56(1): p. 105-16
  4. Satoh R,Fujita Y,Nakashima K,Shinozaki K,Yamaguchi-Shinozaki K
    A novel subgroup of bZIP proteins functions as transcriptional activators in hypoosmolarity-responsive expression of the ProDH gene in Arabidopsis.
    Plant Cell Physiol., 2004. 45(3): p. 309-17
  5. Deppmann CD, et al.
    Dimerization specificity of all 67 B-ZIP motifs in Arabidopsis thaliana: a comparison to Homo sapiens B-ZIP motifs.
    Nucleic Acids Res., 2004. 32(11): p. 3435-45
  6. Contento AL,Kim SJ,Bassham DC
    Transcriptome profiling of the response of Arabidopsis suspension culture cells to Suc starvation.
    Plant Physiol., 2004. 135(4): p. 2330-47
  7. Walter M, et al.
    Visualization of protein interactions in living plant cells using bimolecular fluorescence complementation.
    Plant J., 2004. 40(3): p. 428-38
  8. Nawy T, et al.
    Transcriptional profile of the Arabidopsis root quiescent center.
    Plant Cell, 2005. 17(7): p. 1908-25
  9. Ehlert A, et al.
    Two-hybrid protein-protein interaction analysis in Arabidopsis protoplasts: establishment of a heterodimerization map of group C and group S bZIP transcription factors.
    Plant J., 2006. 46(5): p. 890-900
  10. Deppmann CD,Alvania RS,Taparowsky EJ
    Cross-species annotation of basic leucine zipper factor interactions: Insight into the evolution of closed interaction networks.
    Mol. Biol. Evol., 2006. 23(8): p. 1480-92
  11. Weltmeier F, et al.
    Combinatorial control of Arabidopsis proline dehydrogenase transcription by specific heterodimerisation of bZIP transcription factors.
    EMBO J., 2006. 25(13): p. 3133-43
  12. Kaminaka H, et al.
    bZIP10-LSD1 antagonism modulates basal defense and cell death in Arabidopsis following infection.
    EMBO J., 2006. 25(18): p. 4400-11
  13. Osuna D, et al.
    Temporal responses of transcripts, enzyme activities and metabolites after adding sucrose to carbon-deprived Arabidopsis seedlings.
    Plant J., 2007. 49(3): p. 463-91
  14. Peng M,Bi YM,Zhu T,Rothstein SJ
    Genome-wide analysis of Arabidopsis responsive transcriptome to nitrogen limitation and its regulation by the ubiquitin ligase gene NLA.
    Plant Mol. Biol., 2007. 65(6): p. 775-97
  15. Usadel B, et al.
    Global transcript levels respond to small changes of the carbon status during progressive exhaustion of carbohydrates in Arabidopsis rosettes.
    Plant Physiol., 2008. 146(4): p. 1834-61
  16. Weltmeier F, et al.
    Expression patterns within the Arabidopsis C/S1 bZIP transcription factor network: availability of heterodimerization partners controls gene expression during stress response and development.
    Plant Mol. Biol., 2009. 69(1-2): p. 107-19
  17. Oh SI, et al.
    The Arabidopsis calcium sensor calcineurin B-like 3 inhibits the 5'-methylthioadenosine nucleosidase in a calcium-dependent manner.
    Plant Physiol., 2008. 148(4): p. 1883-96
  18. Saez A,Rodrigues A,Santiago J,Rubio S,Rodriguez PL
    HAB1-SWI3B interaction reveals a link between abscisic acid signaling and putative SWI/SNF chromatin-remodeling complexes in Arabidopsis.
    Plant Cell, 2008. 20(11): p. 2972-88
  19. Kirchler T, et al.
    The role of phosphorylatable serine residues in the DNA-binding domain of Arabidopsis bZIP transcription factors.
    Eur. J. Cell Biol., 2010 Feb-Mar. 89(2-3): p. 175-83
  20. Kang SG,Price J,Lin PC,Hong JC,Jang JC
    The arabidopsis bZIP1 transcription factor is involved in sugar signaling, protein networking, and DNA binding.
    Mol Plant, 2010. 3(2): p. 361-73
  21. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
  22. Matiolli CC, et al.
    The Arabidopsis bZIP gene AtbZIP63 is a sensitive integrator of transient abscisic acid and glucose signals.
    Plant Physiol., 2011. 157(2): p. 692-705
  23. Song QX, et al.
    Soybean GmbZIP123 gene enhances lipid content in the seeds of transgenic Arabidopsis plants.
    J. Exp. Bot., 2013. 64(14): p. 4329-41
  24. Veerabagu M, et al.
    The interaction of the Arabidopsis response regulator ARR18 with bZIP63 mediates the regulation of PROLINE DEHYDROGENASE expression.
    Mol Plant, 2014. 7(10): p. 1560-77